Intensity-Modulated Proton Therapy Adaptive Planning for Patients with Oropharyngeal Cancer
نویسندگان
چکیده
منابع مشابه
Intensity modulated proton therapy.
Intensity modulated proton therapy (IMPT) implies the electromagnetic spatial control of well-circumscribed "pencil beams" of protons of variable energy and intensity. Proton pencil beams take advantage of the charged-particle Bragg peak-the characteristic peak of dose at the end of range-combined with the modulation of pencil beam variables to create target-local modulations in dose that achie...
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The purpose of the study was to investigate the potential of direct machine parameter optimization (DMPO) to achieve parotid sparing without compromising target coverage in IMRT of oropharyngeal cancer as compared to fluence modulation with subsequent leaf sequencing (IM) and forward planned 2-step arc therapy (IMAT). IMRT plans were generated for 10 oropharyngeal cancer patients using DMPO and...
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Purpose: The physical properties of proton therapy allow for decreased dose delivery to nontarget structures. The purpose of this study was to determine if this translates into a clinical benefit by comparing acute and chronic morbidity between patients with nasopharyngeal carcinoma who are treated with intensity-modulated proton therapy (IMPT) and those treated with intensity-modulated radiati...
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Radiation therapy is a non-invasive treatment modality for cancer patients. Radiation therapy treatment planning for cancer patients provides many challenging optimization problems. Various variables of a treatment plan need to be optimized so that the resulting plan can kill all cancerous cells while minimizing damage on the patient’s normal tissues. Intensity modulated proton therapy (IMPT) h...
متن کاملDosimetric predictors of hypothyroidism in oropharyngeal cancer patients treated with intensity-modulated radiation therapy
BACKGROUND Radiation to the neck has long been associated with an elevated risk of hypothyroidism development. The goal of the present work is to define dosimetric predictors of hypothyroidism in oropharyngeal cancer (OPC) patients treated with intensity-modulated radiation therapy. METHODS Data for 123 patients, with a median follow up of 4.6 years, were retrospectively analyzed. Patients wi...
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ژورنال
عنوان ژورنال: International Journal of Particle Therapy
سال: 2017
ISSN: 2331-5180
DOI: 10.14338/ijpt-17-00010.1